幸尚平

幸尚平

中药学博士，2022年以优秀博士毕业于广州中医药大学中药资源科学与工程研究中心-岭南中药资源教育部重点实验室。2022年7月入职登入入口中药学教研室，从事教学和科研工作。主要研究方向为肿瘤分子靶向治疗，中药抗肿瘤分子机制研究。作为项目骨干参与并完成中央本级重大增减支项目、国家自然科学基金项目、广东省自然科学基金等多个项目，目前以第一作者和通讯作者身份发表SCI文章6篇。

代表性研究成果：

1. Shangping Xing, Feifei Nong, Yaqin Wang, Da Huang, Jialiang Qin, Yu-Fei Chen, Dan-Hua He, Pei-En Wu, Huicai Huang, Ruoting Zhan, Hui Xu, Yong-Qiang Liu*. Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis. Pharmacological Research. 2022, 176:106059. （第一作者）

2. Shangping Xing, Feifei Nong, Jialiang Qin, Huicai Huang, Ruoting Zhan, Weiwen Chen*. Gentiopicroside produces endothelium-independent vasodilation by deactivating the PI3K/Akt/Rho-Kinase pathway in isolated rat thoracic aorta. BioMed Research International. 2021, 2021:5565748. （第一作者）

3. Longkai Zhang^#, Weibin Lin^#, Xiaodan Chen, Gang Wei, Hailong Zhu*, Shangping Xing*. Tanshinone IIA reverses EGF- and TGF-β1-mediated epithelial-mesenchymal transition in HepG2 cells via the PI3K/Akt/ERK signaling pathway. Oncology Letters. 2019, 18(6):6554-6562. （通讯作者）

4. Shangping Xing, Xiaofeng Zhang, Hannu Ke, Ji Lin, Yuechun Huang, Gang Wei*. Physicochemical properties of polysaccharides from Dendrobium officinale by fractional precipitation and their preliminary antioxidant and anti-HepG2 cells activities in vitro. Chemistry Central Journal. 2018, 12(1):100. （第一作者）

5. Shangping Xing^#, Wenxia Yu^#, Xiaofeng Zhang, Yingyi Luo, Zhouxi Lei, Dandan Huang, Ji Lin, Yuechun Huang, Shaowei Huang, Feifei Nong, Chunhua Zhou, Gang Wei*. Isoviolanthin extracted from Dendrobium officinale reverses TGF-β1-mediated epithelial-mesenchymal transition in hepatocellular carcinoma cells via deactivating the TGF-β/Smad and PI3K/Akt/mTOR signaling pathways. International Journal of Molecular Sciences. 2018, 19(6):1556. （第一作者）

6. Lihua Yang^#, Shangping Xing^#, Kun Wang, Hua Yi*, Biaoyan Du*. Paeonol attenuates aging MRC-5 cells and inhibits epithelial-mesenchymal transition of premalignant HaCaT cells induced by aging MRC-5 cell-conditioned medium. Molecular and Cellular Biochemistry. 2018, 439(1-2):117-129. （共同第一作者）